Guangdong, China
Business Type:
Manufacturer/Factory
Registered Capital:
20000000 RMB
Plant Area:
1001~2000 square meters
Management System Certification:
ISO 9001, GMP
Average Lead Time:
Peak season lead time: more than 12 months
Off season lead time: within 15 workdays
Sample Available

Beta-Nmn Beta - Nicotinamide Mononucleotide, Nicotinamide, Mononucleotide manufacturer / supplier in China, offering Beta-Nmn Beta - Nicotinamide Mononucleotide Prevention of Skin Diseases & for Anti Aging 1094-61-7, Multi Blend Deca Liquid Tri Deca 300mg/Ml for Gain Muscle, Stainless Steel  Hand Using Cap Crimper for Vials Sealing and so on.

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Beta-Nmn Beta - Nicotinamide Mononucleotide Prevention of Skin Diseases & for Anti Aging 1094-61-7

Get Latest Price
Min. Order / Reference FOB Price
5 g US $6/ g
Port: Hong Kong, Hong Kong
Production Capacity: 50000pieces/Year
Payment Terms: T/T, Western Union, Money Gram
Powder: Yes
Customized: Non-Customized
Certification: GMP, ISO 9001, USP, BP
Suitable for: Adult
State: Solid
Purity: >99%

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Basic Info

Model NO.
Nicotinamide
Trademark
xin hang
Transport Package
as Requirement
Specification
as requirement
Origin
China
HS Code
3601000010

Beta-Nmn Beta - Nicotinamide Mononucleotide Prevention of Skin Diseases & for Anti Aging 1094-61-7
Cosmetic Powder BETA-NMN Beta - Nicotinamide Mononucleotide for Anti Aging 1094-61-7


Product Name: BETA-NICOTINAMIDE MONONUCLEOTIDE 
Synonyms: BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE;NICOTINAMIDE RIBOTIDE;NICOTINAMIDE MONONUCLEOTIDE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium 
CAS: 1094-61-7 
MF: C11H15N2O8P 
MW: 334.22 
EINECS: 214-136-5 
Product Categories: Amines;Aromatics;Bases & Related Reagents;Intermediates & Fine Chemicals; Derivatives;Nucleotides;Pharmaceuticals
Storage temp.  2-8°C
Chemical Properties : White Solid 
Usage A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation . 

 

Beta-Nmn Beta - Nicotinamide Mononucleotide Prevention of Skin Diseases & for Anti Aging 1094-61-7

 β-Nicotinamide mononucleotide Description

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic  sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. It is to be used for research only.


Beta-Nicotinamide Mononucleotide Application

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.

NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth. However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.


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Beta-Nmn Beta - Nicotinamide Mononucleotide Prevention of Skin Diseases & for Anti Aging 1094-61-7
Beta-Nicotinamide Mononucleotide COA

ITEMS STANDARD RESULTS
Producr Name Beta-nicotinamide Mononucleotide
Purity Beta-nicotinamide Mononucleotide≥98% 99.6%
Contents (Anhydrous Basis) ------ 97.1%
Appearance White to yellowish lyophilized powder Conforms
Odor Characteristic Conforms
Mesh Size 100% pass 80 Mesh Conforms
Water contents <8.0% 4.6%
PH(10mg/ml) 2-4 2.7
Pb <10ppm Conforms
Fe <10ppm Conforms
Cu <10ppm Conforms
Al <10ppm Conforms
Conclusion Conform with specification

Beta-Nmn Beta - Nicotinamide Mononucleotide Prevention of Skin Diseases & for Anti Aging 1094-61-7

 

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